Dr Stefano Del Giacco
It is well recognized that atopic sensitisation is an important risk factor for asthma, both in adults and in children. However, the potential role of allergy in severe asthma is still under debate. The term “Severe Asthma” encompasses a highly heterogeneous group of patients who require treatment on steps 4–5 of GINA guidelines to prevent their asthma from becoming "uncontrolled", or whose disease remains "uncontrolled" despite this therapy. Epidemiological studies on emergency room visits and hospital admissions for asthma suggest the important role of allergy in asthma exacerbations, and allergic asthma in childhood is often associated with severe asthma in adulthood. A strong association of asthma exacerbations with respiratory viral infections has been demonstrated, and the interaction between viruses and allergy was shown to increase the risk of asthma exacerbations. Fungal allergy may also play an important role in severe asthma while cofactors such as smoking, pollution and work-related exposures must always be considered. In this plenary Stefano Del Giacco will provide an overview about the role of allergy in severe asthma and the importance of the main co-factors in this link.
Go to 5:45 mins to view Allergies & Severe Asthma presentation.